American Medical Systems Receives CE Mark for AdVance(R) Xtra Performance (XP) Male Sling System

By American Medical Systems Inc., PRNE
Monday, August 23, 2010

MINNETONKA, Minnesota, August 24, 2010 - American Medical Systems(R) (AMS) (Nasdaq: AMMD), a leading provider of
world-class devices and therapies for both male and female pelvic health,
announced today the company received CE (Conformite Europeenne) Mark for
AdVance XP. The device is the latest generation of AMS' AdVance sling, a
minimally invasive implant for the treatment of male stress urinary
incontinence (SUI). Male SUI is an unfortunate and common side effect of
prostate cancer and benign prostatic hyperplasia (BPH) treatments, such as
radical prostatectomy and transurethral resection of the prostate (TURP).

Built on the trusted success of the AdVance platform, AdVance XP
incorporates additional features that are designed to deliver Xtra
Performance for improved ease-of-use and clinical outcomes. Enhancements
include a redesigned sling that incorporates a new mesh designed to improve
procedural reproducibility, longer arms that are easier to use in larger
patients and distinct tissue anchors that increase holding power during the
critical healing period, following implantation.

"With AdVance XP, we are solidifying our best-in-class male sling
status," said Whitney Erickson, vice president and general manager for men's
health at AMS. "These enhanced features are designed to provide improvements
to the AdVance male sling platform that lead to even greater reliability and
procedural consistency."

The first AdVance XP implant was performed by Professor Francois Haab on
July 12 at Tenon Hospital in Paris, France. "The AdVance XP sub-urethral
sling is a substantial and positive evolution of the existing AdVance sling,"
Haab commented. "AdVance XP maximizes the already very satisfactory results
that have been published with AdVance."

AMS has launched AdVance XP with a focused group of urologists throughout
Europe with full-scale launch anticipated by the end of the year. AMS has
filed for Food and Drug Administration (FDA) clearance. Pending required
regulatory clearances, U.S. commercialization will commence.

For more information about AdVance, visit
www.americanmedicalsystems.com.

About American Medical Systems:

American Medical Systems, headquartered in Minnetonka, Minnesota, is a
diversified supplier of medical devices and procedures to cure incontinence,
erectile dysfunction, benign prostate hyperplasia (BPH), pelvic floor repair
and other pelvic disorders in men and women. These disorders can
significantly diminish one's quality of life and profoundly affect social
relationships. In recent years, the number of people seeking treatment has
increased markedly as a result of longer lives, higher-quality-of-life
expectations and greater awareness of new treatment alternatives. American
Medical Systems' products reduce or eliminate the incapacitating effects of
these diseases, often through minimally invasive therapies. The Company's
products were used to treat approximately 335,000 patients in 2009.

More information about the Company and its products can be found at its
website www.AmericanMedicalSystems.com and in the Company's Annual
Report on Form 10-K for 2008 and its other SEC filings.

Media, Lisa Kornblatt of SS|PR, +1-847-415-9330, lkornblatt at sspr.com; or Investor Relations, Mark Heggestad of American Medical Systems, +1-952-930-6495, mark.heggestad at AMMD.com

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