Geth And Pethema

LONDON, June 10, 2011 - - New data presented at the European Hematology Association (EHA) 2011 Annual Meeting in London show better control of nausea and vomiting with the combination palonosetron plus aprepitant when compared to granisetron in patients receiving multiday highly emetogenic conditioning chemotherapy regimens - Significantly higher the complete response during the acute, delayed and overall periods The combination of palonosetron (0.25 mg iv every 48 h) and aprepitant (125 mg on day 1, followed by 80 mg each of the remaining days) improves control of CINV (Chemotherapy Induced Nausea and Vomiting) compared with daily granisetron (3 mg iv) during the conditioning period (5-6 days) of patients prior to stem cell transplantation (HSCT).