Bostonedison
BOSTON and EDISON, New Jersey -
-- Pharmacokinetic Analysis of Atrial Fibrillation Study May Explain Bleeding Rate Difference between Once-Daily and Twice-Daily Dosing Regimens with Same Total Exposure of Factor Xa Inhibitor --
A sub-analysis of a Phase IIb multinational study(1) with edoxaban(2) -- an investigational oral Factor Xa inhibitor - provides insights into why patients with non-valvular atrial fibrillation (AF) receiving edoxaban once daily (OD) experienced fewer bleeding events than patients given edoxaban twice a day (BID).