Mainstay of the Global Workforce - 40-65 Year Olds - Hit Hardest by Chronic Obstructive Pulmonary Disease (COPD)

New Report Highlights Global Economic Burden of the Disease

LONDON, November 18 - COPD Uncovered, a new report issued today reveals for the first time that
people between the ages of 40 to 65 are emerging as the new face of this
disease. Authored by Education for Health and other leading experts, the
report uncovers a new, younger majority of COPD patients(1) who are in the
prime of their career, and financially responsible for the care of their
children and aging parents. The authors call for policymakers to read the
report and challenge their thinking on how COPD should be addressed in this
critical age group who are highly depended upon by society as leading wage
earners(2,3).

COPD affects 210 million people and is predicted to be the third leading
cause of death globally in ten years time(4). A severely debilitating
disease, COPD dramatically impairs the productivity of this population. In
fact, the report found that people between 40 and 65 with COPD miss as many
as ten hours of work per week because of their condition(5). On a global
scale, that represents more than two billion working hours lost each week
worldwide. Additionally, COPD causes nearly 28,000 years of lost productivity
annually(6). The report deduces that if left unchecked, COPD could have
significant global workforce and economic implications on patients, families,
employers and society as the disease escalates.

"Given the potential economic impact, it is critical that 40 to 65 year
olds with COPD are able to lead an active and productive life," said Monica
Fletcher, Chief Executive of Education for Health. "In releasing this report
we want to spark an important global dialogue with key global stakeholders on
how best to invest in earlier diagnosis and the management of these younger
patients."

Other key insights from the report include:

    - COPD costs more than asthma and diabetes - The cost of COPD
      exceeds that of many other serious, long-term conditions including
      asthma and diabetes(7). The worldwide burden of COPD is nearly double
      that of diabetes and it causes more deaths(6).

    - Effective COPD treatment must look beyond smoking cessation - It is
      true that the primary cause of COPD is cigarette smoke(8) and smoking
      cessation is an important part of COPD management. Yet many former
      smokers develop symptoms and are diagnosed a decade or two after they
      stopped. In fact, even if all smoking stopped today, the effect on COPD
      statistics would not be seen for up to 20 years(9).

    - COPD puts pressure on healthcare systems - One in six
      European and U.S. patients had visited the ER or hospital in a six
      month period 2006-20075. Extrapolating these figures indicates that up
      to 64 million COPD patients globally may be admitted to hospital due to
      their condition each year. Additionally, a large majority of COPD
      patients suffer from co-morbidities, such as heart disease, high blood
      pressure and diabetes(10-13). In fact, 40 percent suffer from heart
      disease10 and as many as 42 percent from high blood pressure(12,13).
    - Families may also face burden - More women than men are now being
      be diagnosed with COPD(14) - a patient segment central to family care.

About COPD

Chronic obstructive pulmonary disease (COPD) is a debilitating,
life-threatening and progressive lung disease that interferes with normal
breathing(8). It is thought to cause around three million deaths per year -
on average one person every 10 seconds(4). COPD refers to emphysema and
chronic bronchitis - two commonly co-existing diseases of the lung. Due to
lung deterioration, people with COPD experience symptoms like chronic
shortness of breath and cough that impact the ability to lead an active and
productive life(8). There is no cure for COPD but it can be treated.

About COPD Uncovered

COPD Uncovered represents the combined efforts of a multi-disciplinary
committee of international experts, coming together to bring forward some of
the most burning issues in COPD today. Their aim is to highlight the impact
of COPD in an understudied and ignored patient segment between the ages of 40
and 65.

The COPD Uncovered initiative is a compendium of research and analysis
undertaken by experts in respiratory health. This initiative is sponsored by
Novartis Pharma AG and is administered by a Secretariat from Chandler Chicco
Companies (CCC). The studies underlying the COPD Uncovered Report were
commissioned by Novartis Pharma AG.

Following the release of this report, the COPD Uncovered experts are
conducting further quantitative research into the direct and indirect costs
of the disease among this age group. In 2010, they expect to release the
results of the study that will look at the specific impact of COPD on the
daily lives of more than 2,000 COPD patients aged 45-67 from the U.S., the
UK, Germany, Brazil, China and Turkey.

About the Authors

The COPD Uncovered Report, issued on World COPD Day 2009, is authored by
the following individuals, supported by Novartis with editorial assistance
from medical education specialists from CCC:

    - Monica Fletcher, Chief Executive, Education for Health and National
      Respiratory Training Center, principle lead for COPD Uncovered

    - Dr Marianella Salapatas, President, European Federation of Allergy and
      Airways Diseases Patients' Associations

    - Professor Thys van der Molen, Department of General Practice,
       University of Groningen

    - John Walsh, President and CEO, COPD Foundation

    To download a copy of the COPD Uncovered report, visit:

    bit.ly/3n99Yu

References:

www.educationforhealth.org.uk/pages/_documents/COPD_Release.pdf

    For press enquiries, please contact:

    Sue Davis Russell - PA to Chief Executive
    Education for Health
    Tel: +44-(0)1926-836841, Email: s.davisrussell@educationforhealth.org

    Candy Perry - Head of Corporate Communications and External Affairs
    Education for Health
    Tel: +44-(0)1926-836995, Email: c.perry@educationforhealth.org

Visit our website at: www.educationforhealth.org

For press enquiries, please contact: Sue Davis Russell - PA to Chief Executive Education for Health, Tel: +44-(0)1926-836841, Email: s.davisrussell at educationforhealth.org. Candy Perry - Head of Corporate Communications and External Affairs, Education for Health, Tel: +44-(0)1926-836995, Email: c.perry at educationforhealth.org