Concentric Medical Receives Shonin Approval for Merci Retriever(R) in Japan

MOUNTAIN VIEW, California, May 4, 2010 - Concentric Medical, Inc., the global leader in devices for clot removal
in ischemic stroke patients, today announced that the Merci Retriever(R),
Merci(R) Microcatheter, and Merci(R) Balloon Guide Catheter have received
Shonin approval in Japan. The Merci Retriever is a catheter-based medical
device that stroke centers use to remove blood clots from the brains of
patients suffering an ischemic stroke. Century Medical Inc. of Japan is
Concentric Medical's distribution partner. The two companies have worked
together to obtain Shonin approval.

Nobuyuki Sakai, M.D., D.M.Sc., Director, Neurosurgery & Stroke Center at
Kobe General Hospital said, "The approval of the first endovascular device in
Japan for acute ischemic stroke patients is a humbling reminder of the
importance of a physician's responsibility to perform endovascular
treatments. Current treatment for acute ischemic stroke in Japan has been
limited to IV-tPA. With the addition of the Merci Retriever as a treatment
option, we have the opportunity to save more lives. In Japan, we intend to
quickly establish treatment protocols with the Merci Retriever and share our
clinical experience with our colleagues around the world."

Maria Sainz, President and CEO of Concentric Medical said, "The
opportunity to provide the first approved mechanical clot retrieval
technology to Japanese physicians for acute ischemic stroke patients is a
highly significant milestone and represents an exciting opportunity for
Concentric Medical. We are committed to working closely with Japanese
clinicians to help advance stroke care with the Merci Retriever. Our clinical
data and experience outside of Japan gives Concentric a solid platform to
successfully introduce the Merci Retriever to the Japanese market."

Akira Hoshino, President and CEO of Century Medical said, "Over 250,000
people suffer a stroke every year in Japan. Obtaining Shonin approval for the
Merci Retriever marks a great achievement in the advancement of
interventional stroke care for both Japanese physicians and patients. Century
Medical is committed to working with physicians and hospitals throughout
Japan to make the Merci Retriever widely available for Japanese stroke
patients."

About Concentric Medical

Concentric Medical is located in Mountain View, California and is the
global leader in the development of endovascular devices for revascularizing
stroke patients. The company manufactures and markets solutions for ischemic
stroke: minimally invasive devices that are delivered into the brain to
restore blood flow by removing blood clots that cause ischemic stroke.
Concentric Medical's devices are available in over 500 leading stroke centers
around the world, and have been the subject of several clinical studies. For
more information about Concentric Medical, please visit
www.concentric-medical.com.

About Acute Ischemic Stroke

Stroke is the third leading cause of death in the developed world and the
leading cause of serious long-term disability. Ischemic stroke represents
over 85% of strokes and occurs when a blockage or clot develops in one of the
arteries supplying blood to the brain. In 2004 the FDA cleared Concentric
Medical's Merci Retriever(R) for use in patients who are ineligible for
IV-tPA or who fail to respond to IV-tPA therapy. This pioneering device
creates a departure from the historic method of caring for stroke patients
and offers physicians and patients a long-awaited option for stroke
intervention.

    Media Contact: Scott Meggs, Corporate Counsel
    +1-650-938-2100
    strokeinfo@concentric-medical.com

Scott Meggs, Corporate Counsel of Concentric Medical, +1-650-938-2100, strokeinfo at concentric-medical.com