IFRA Issues Fragrance Standards Update

BRUSSELS, June 27, 2011 -

The International Fragrance Association (IFRA) has officially
issued the 46^th Amendment to the IFRA Code of Practice
as part of the industry’s ongoing safety program*.

There are six new restrictive Standards based on the
Quantitative Risk Assessment (QRA)** and one new Standard
prohibiting the use of 2,4-Octadienal.

IFRA has also withdrawn the Standard for Vanillin, which was
first put in place with the 44^th Amendment. This
Standard was put on hold on 1^st December, 2009, has now
been officially withdrawn. Following the Vanillin Standard’s
notification additional information was submitted, which allowed
for a re-evaluation of the material. After further additional
testing and a critical evaluation of all available data today, IFRA
has decided to withdraw the Standard and not set a revised
Standard.

IFRA has also updated various guidance documents as part of the
46^th Amendment.

• QRA Information Booklet Version 6.0 Final 2011 (including
  guidance on classes for IFRA Certificates)
• Annex 1 to the IFRA Standards which has been updated with
  contributions from other sources for o-Methoxycinnamaldehyde and
  Safranal
• Index (list of all IFRA Standards)
• Standard Operating Procedures (SOP) for the implementation of
  IFRA Standards

All the new Standards and related guidance documents are freely
available on the IFRA website: href="www.ifraorg.org">www.ifraorg.org

1.    Six new Standards, based on the
QRA

       CAS             Name                                      Status

    7492-44-6     alpha-Butylcinnamaldehyde
    39189-74-7    2-Heptylidene cyclopentan-1-one                  NEW
    1504-74-1     o-Methoxycinnamaldehyde                       RESTRICTED
    68922-13-4    3-Methyl-2-(pentyloxy)cyclopent-2-en-1-one      (QRA)
    13257-44-8    2-Nonyn-1-al dimethyl acetal
    13144-88-2    1-(2,4,4,5,5-Pentamethyl-1-cyclopenten-1-yl)
                  ethan-1-one

2.    One new Standard
prohibiting the use of 2,4-Octadienal

2,4-Octadienal has been reviewed by the RIFM Expert Panel and,
due to lack of adequate data (Dermal DNA Adduct study), it was
concluded that it should not be used as or in fragrance ingredients
in whatever application until additional data is available and
considered sufficient to support its use. The presence of a
structural alert as defined in the Human Health Criteria Document
justifies this ban which already concerns several materials of the
same structural family.

       CAS           Name                     Status

    30361-28-5    2,4-Octadienal            PROHIBITED

Notes to Editors:

*Fragrance industry Safety Program

The fragrance industry’s safety program is founded on testing
fragrance materials and either establishing ‘Safe Use Levels’, or
prohibiting their use, based on studying their potential effects on
people and the environment. Currently the safety program contains
186 ‘Standards’, which restrict, or prohibit, the use of selected
fragrance materials.

To ensure that the fragrance industry adheres to its safety
standards the International Fragrance

Association (IFRA) has a Compliance Program. Every year 50
products from a selection of 450, gathered from stores in 10
different countries, are tested. If a product does not comply with
its Code of Practice and Standards, IFRA works with the
manufacturer to ensure compliance.

The IFRA Code of Practice is a comprehensive document that
supports the IFRA commitment to provide products that are safe for
use by the consumer and to the environment.

The Code of Practice applies to the manufacture and handling of
all fragrance materials, for all types of applications and contains
the full set of IFRA Standards. Abiding by the IFRA Code of
Practice is a prerequisite for all fragrance supplier companies
that are members of IFRA (either directly or through national
associations). The majority of client companies (including
producers of toiletries and household products) expect their
fragrances to comply with IFRA Standards as set out in the
Code.

The IFRA Code of Practice is distributed worldwide and is in the
hands of all member associations and their member companies, in
addition to governmental regulatory bodies and many other
stakeholders. It is also available to all on our website: href="www.ifraorg.org">www.ifraorg.org

**Quantitative Risk Assessment
(QRA)

In 2005 IFRA introduced a new Quantitative Risk Assessment or
QRA approach to restrict fragrance materials that have a potential
to induce contact sensitization. This new approach is a much more
refined approach for evaluating sensitizing materials, and so
provides more precise guidance on use levels of materials depending
on the situation and the product in which they are used; ultimately
it should better protect the consumer from becoming sensitized to a
specific material.

For more information, please contact: Contact person: Stephen Weller, Company: IFRA, Phone number: +32-2-214-2067, Mobile number: +32-497-57-33-94, E-mail address: sweller at ifraorg.org