Ingenuity Systems and Erasmus University Medical Center Collaborate on Next-Generation Sequencing Project to Accelerate Disease Research

IPA(R) used to identify and prioritize novel causal variant

REDWOOD CITY, California, January 18, 2011 - Ingenuity(R) Systems, a leading provider of information solutions for
life science researchers, and Erasmus Medical Center, jointly announced a
scientific collaboration using next-generation sequencing (NGS) for disease
research.

As part of the collaboration, Erasmus researchers have been working
closely with Ingenuity to derive the most impactful biological insights from
their NGS data. Using Ingenuity's IPA software and the Ingenuity(R) Knowledge
Base, Erasmus MC researchers are able to map and contextualize genes and
variants related to biological processes, functions, diseases, pathways,
compounds, and relationships, and obtain a more complete biological picture
from their NGS data.

"Like many researchers, we faced the challenge of sifting through
thousands of variants in order to rapidly identify the few that were the best
candidates for follow-up studies and those most likely to be causal for our
disease phenotype," said Professor Peter van der Spek, Ph.D., Erasmus
University Medical Center. "IPA helped us overcome this challenge and
discover a novel causal variant in a disease area of interest. It provides
the critical biological context necessary to realize the full potential of
NGS datasets, thanks to its high-quality, detailed biomedical content and
powerful analysis capabilities. We're excited about Ingenuity's investments
and capabilities in the NGS space and look forward to our continued
partnership."

"We are honored to collaborate with Erasmus University Medical Center on
their NGS programs, and pleased they were able to obtain their desired
results so quickly with IPA," said Doug Bassett, Ph.D, Chief Scientific
Officer and Chief Technology Officer, Ingenuity Systems. "We're excited to
see this validation of IPA's role in NGS research and its ability to provide
meaningful insights for researchers leveraging NGS data. We're looking
forward to our ongoing collaboration and translating the results of this
collaboration into new product capabilities."

About Ingenuity(R) Systems

Ingenuity Systems is a leading provider of information solutions and
custom services for life science researchers, computational biologists and
bioinformaticists, and life science industry suppliers. For more information
visit: www.ingenuity.com

About Erasmus University Medical Center Rotterdam

Erasmus MC is the largest and most authoritative scientific University
Medical Center in the Netherlands. Almost 13,000 staff members work within
the core tasks of patient care, education, and scientific research on the
continuous improvement and enforcement of individual patient care and social
healthcare. They develop high-level knowledge, pass this on to future
professionals, and apply it in everyday patient care. Over the next five
years, Erasmus MC wants to grow into one of the best medical institutes in
the world. Erasmus MC is part of the Dutch Federation of University Medical
Centers (NFU). See www.nfu.nl

Heidi Bullock, Director, Marketing of Ingenuity Systems, +1-650-381-5150