Ingenuity Systems and Geospiza Collaborate to Create Seamless Next-Generation Sequencing Workflow

By Ingenuity Systems, PRNE
Tuesday, November 2, 2010

REDWOOD CITY, California, November 3, 2010 - Ingenuity(R) Systems, a leading provider of information solutions for
life science researchers, and Geospiza, Inc., the market leading developer of
laboratory management and genetic analysis software, today announced a
collaboration to enable a seamless next-generation sequencing analysis
workflow. The companies will integrate their software products, GeneSifter(R)
and IPA(R), to enable researchers to obtain deep biological insights from
their project samples through a rapid and reliable workflow to analyze and
visualize next-generation sequencing data.

"This is a perfect synthesis of expertise, in my opinion," says
Christopher Mason, Ph.D., Professor of Computational Genomics at the
Institute for Computational Biomedicine at Weill Cornell Medical College
(WCMC), and a member of the Tri-Institutional Program on Computational
Biology and Medicine of WCMC, Rockefeller, and Memorial Sloan-Kettering
Cancer Center. "Geospiza has already worked with every modality of sequencing
from every known platform, and will work with all of the emerging
technologies. They have shown that they can easily convert raw data to
per-base dynamics, and the logical next step for contextualizing genetic,
epigenetic, transcriptional, and/or proteomic common and rare variation is to
overlay these changes within the known and predicted pathways and drug
targets that are well-annotated and curated by Ingenuity. I can't wait to use
their merged tools and databases."

"The promise of NGS is dependent on a researcher's ability to quickly and
accurately distill millions of reads and hundreds of datasets down to a
manageable list of the most interesting and relevant genes," stated Todd
, CTO, Geospiza. "Our integration with IPA will accelerate drug
discovery and 'omics research pipelines by enabling NGS researchers to
understand and visualize their data in the context of known biological
processes, functions, diseases, pathways and relationships, through IPA's
powerful analysis capabilities and the timely, detailed information in the
Ingenuity(R) Knowledge Base."

"Our main objective is to help our joint customers confidently answer
their research questions in a relevant biological context," stated Doug
, Ph.D., CSO and CTO, Ingenuity Systems. "It is important to provide a
streamlined way for researchers to move from a list of genes, isoforms, or
variants all the way to identifying drug targets, validating biomarkers,
generating hypotheses, and understanding drug mechanism of action. IPA
supports multiple data types, disease areas, and experimental platforms, and
the GeneSifter and IPA integration continues to strengthen this focus by
offering a complete and reliable platform for the analysis and interpretation
of NGS data."

About Ingenuity(R) Systems

Ingenuity Systems is a leading provider of information solutions and
custom services for life science researchers, computational biologists and
bioinformaticists, and life science industry suppliers. For more information

About Geospiza

Designed by biologists, Geospiza's products are configured to reflect
best practices and to work out-of-the-box, so that researchers can focus on
their science. Geospiza's software systems have established an international
reputation for quality, usability and reliability since 1997. You can find
more information on Geospiza and its products at

Heidi Bullock, Director, Marketing of Ingenuity Systems, +1-650-381-5150

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