Nordion Reports Fourth Quarter and Fiscal 2010 Financial Results

By Nordion Inc., PRNE
Thursday, January 20, 2011

Improved Performance Across All Business Segments

OTTAWA, January 21, 2011 -

    Highlights:

    - Resumed position as a key supplier in the molybdenum-99 (Mo-99) supply
      chain with the restart of the National Research Universal (NRU) reactor
    - Established long-term supplemental supply of Mo-99 with Russian
      supplier, Isotope
    - Ended fiscal 2010 in a solid liquidity position and with financial
      flexibility, announcing dividend and Normal Course Issuer Bid (NCIB)
      program in January 2011
    - Initiated reporting on three segments: Medical Isotopes, Targeted
      Therapies, and Sterilization Technologies

- Nordion reports in U.S. dollars unless otherwise specified

Nordion Inc. (TSX: NDN; NYSE: NDZ), a leading provider of products and
services to the global health science market, today reported its fourth
quarter and fiscal 2010 financial results. The Company also filed its 2010
Annual Report, which includes audited consolidated financial statements and
notes for the year ended October 31, 2010, and related management's
discussion and analysis, the 2010 Annual Information Form, and the 2011
Management Proxy Circular.

Revenues from continuing operations of $85.8 million were up $34.4
million
or 67% in the fourth quarter of fiscal 2010, compared with $51.4
million
in the fourth quarter of fiscal 2009. Income from continuing
operations was $9.3 million ($0.14 earnings per share), compared with a loss
of $18.2 million ($0.14 loss per share) in the fourth quarter of fiscal 2009.

In fiscal 2010, revenues from continuing operations were $240.4 million,
up 4% compared with fiscal 2009. The loss from continuing operations was
$103.3 million ($1.16 loss per share), a significant increase from a loss of
$11.7 million ($0.10 loss per share) in fiscal 2009.

"Nordion's financial results strengthened in the fourth quarter across
all three business segments," said Mr. Steve West, Chief Executive Officer,
Nordion Inc. "Increased sales in the Sterilization Technologies business, a
resumption of activity in the Mo-99 supply chain, and improved performance of
key Targeted Therapies products contributed to stronger revenues."

"Now that Nordion has completed the strategic repositioning, we're
focused on driving improved profitability and cultivating sustainable
growth," added Mr. West.

    Key Q4 Events:

    - Nordion extended its existing agreement with Ontario Power Generation,
      Inc., securing supply of cobalt-60 (Co-60) for the Company until 2020.

    - The NRU reactor, Nordion's primary source of Mo-99 supply, returned to
      operation and Nordion resumed its role in the medical isotope supply
      chain.

    - Nordion announced that Kenneth Newport was appointed to the Board of
      Directors.

    - Nordion entered into a framework agreement with Russian Rosatom State
      Corporation's subsidiary, Open Joint Stock Company Isotope (Isotope),
      and signed an agreement for the exclusive supply of Mo-99 for
      processing, distribution and sale outside the Russian Federation until
      2020.

    Subsequent to the quarter:

    - On November 1, 2010, the Company completed its name change from MDS
      Inc. to Nordion Inc.

    - On December 2, 2010, Nordion announced it had signed a non-binding
      letter of intent to divest its Belgian subsidiary, MDS Nordion S.A.

    - On December 23, 2010, Nordion announced that the first sample of Mo-99
      had been shipped from Isotope.

    - On January 5, 2011, Nordion announced it had extended its Mo-99 supply
      contract with a major customer, Lantheus Medical Imaging, Inc., until
      December 31, 2013.

    - On January 20, 2011, Nordion announced the introduction of an annual
      dividend of $0.40 per share, to be payable on a quarterly basis, and an
      NCIB program.

"Nordion demonstrated resilience throughout 2010," said Peter Dans, Chief
Financial Officer. "By focusing on operational and financial performance, the
Company exited the year with the financial flexibility that allows us to
return cash to shareholders through our announced dividend and NCIB."

Medical Isotope Update

The restart of the NRU reactor was a major event for Nordion in the
fourth quarter of fiscal 2010. It supported the Company's return as a key
player in the Mo-99 supply chain and as an important partner to its
customers.

The current medical isotope landscape is significantly different when
compared with the landscape Nordion operated in prior to the NRU reactor
shutdown in May 2009. These changes created uncertainty in the medical
isotope market, in general, and has specifically impacted Nordion. Several
factors, as discussed in the 2010 Management Discussion and Analysis (MD&A)
filed today, have affected key drivers of the Company's profitability of its
Medical Isotopes segment, including pricing and demand for medical isotopes,
and in particular, for Mo-99. As a result, based on activity since the NRU
reactor restarted in late-August 2010, the Company currently expects revenue
and segment earnings contribution for the first and second quarter of fiscal
2011 to be similar to our results for medical isotopes in the fourth quarter
of fiscal 2010. This indicates that lower demand and reduced market share are
expected to offset price increases compared with what it was prior to the May
2009
shutdown. Nordion continues to work with existing customers and is in
discussions with potential new customers to increase its global market share
of Mo-99.

The Company continues to expect to receive its first commercial shipment
of supplemental Mo-99 product from its Russian partner, Isotope, in the first
half of fiscal 2011. Supply is anticipated to be available to partially
offset the impact of an approximately one-month long shutdown of the NRU
reactor scheduled by Atomic Energy of Canada Limited (AECL) in mid-May of
2011. Nordion will not receive product from the NRU reactor for the majority
of the shutdown period. While the anticipated Mo-99 supply from Isotope
during the planned shutdown of the NRU reactor is expected to be
substantially less than the Company currently receives from the NRU reactor,
the agreement with Isotope establishes Nordion as a reliable supplier of
Mo-99 over the mid- to long-term and strengthens its relationships with
customers. Over several years, the expectation is to have supply available of
up to 20% of global Mo-99 demand to back up long-term requirements.

MAPLE Arbitration Update

Hearings for the arbitration with AECL related to the MAPLE Facilities
are proceeding, and the Company currently expects them to conclude in the
fall of 2011, with a decision from the panel following the conclusion of the
hearings.

Fourth Quarter and F2010 Results

                             Three months ended           Twelve months ended
                                     October 31                    October 31
                           2010            2009        2010              2009
    Consolidated
    Results
    (thousands of U.S.
    dollars, except
    where noted)
    Consolidated
    Revenues from
    continuing
    operations        $  85,841          51,411 $   240,352           231,263
    Gross margin            53%             46%         47%               49%
    Operating income
    (loss) from
    continuing
    operations        $  15,394        (11,985)   (106,405)           (1,616)
    Income (loss)
    from continuing
    operations        $   9,280      $ (18,228) $ (103,348)       $  (11,650)
    - Basic earnings
    (loss) per share
    from continuing
    operations        $    0.14      $   (0.14) $    (1.16)       $    (0.10)
    Net income (loss) $  15,672      $ (58,658) $ (232,010)       $ (135,241)
    Cash and cash
    equivalents       $ 122,802      $  298,203 $   122,802       $   298,203
    Share buyback
    - thousands of
    shares                    -               -      52,941                 -
    Weighted average
    number of Common
    shares outstanding
    - basic (thousands
    of shares)           67,237         120,137      89,279           120,137

Continuing Operations by Segment

- Consolidated revenues from continuing operations in the fourth quarter
of fiscal 2010 were $85.8 million, up $34.4 million or 67%, compared with the
fourth quarter of fiscal 2009. The increase was primarily due to higher
revenues from Medical Isotopes as a result of the NRU reactor resuming
operations in August 2010, higher Targeted Therapies revenues primarily due
to increased shipments of TheraSphere(R) and CardioGen-82TM products, and
higher Sterilization Technologies revenues as a result of increased shipments
of Co-60 and the sale of a production irradiator. Gross margin was 53%,
compared with 46% in the fourth quarter of the previous fiscal year.

- Income from continuing operations in the fourth quarter of fiscal 2010
was $9.3 million, up $27.5 million, compared with the fourth quarter of
fiscal 2009. Other than a favourable $13 million change in the fair value of
embedded derivatives primarily associated with the Company's Russian Mo-99
supply agreement, the increase was primarily due to improved segment earnings
from Medical Isotopes and Sterilization Technologies. Additionally, the
Company incurred lower restructuring costs in the fourth quarter of fiscal
2010 compared with in the same quarter in fiscal 2009.

- Other items impacting income from continuing operations in the fourth
quarter of fiscal 2010 also included:

- Selling, general and administrative (SG&A) expenses of $29.3 million,
up $8.4 million compared with the same period of fiscal 2009 primarily due to
a $2.8 million increase in cost associated with the MAPLE arbitration, higher
costs associated with transition activities, higher incentive and stock-based
compensation, and an unfavorable operational foreign exchange impact.

- $2.5 million of restructuring costs primarily related to facilities,
compared with $8.5 million of restructuring charges in the fourth quarter of
fiscal 2009.

- Other expenses, net of $4.0 million, up $5.4 million compared with an
income of $1.4 million the same period of fiscal 2009.

- Cash and cash equivalents of $122.8 million as of October 31, 2010, was
$175.4 million lower compared with $298.2 million as of October 31, 2009, but
up $1.5 million from the end of the third quarter of 2010. Factors impacting
year over year cash balances are described in the liquidity section of the
Company's 2010 MD&A filed today, and include the effects of divestures, share
buybacks, debt settlement, and operational needs. In the fourth quarter of
2010, payments for restructuring costs and income taxes remittances were
funded primarily from positive operational cash flow and the sale of an
Asset-backed commercial paper investment.

Medical Isotopes

                                  Three months ended      Twelve months ended
                                          October 31               October 31
                                 2010           2009     2010            2009
    Consolidated Results
    (thousands of U.S.
    dollars, except where
    noted)
    Revenues                 $ 27,907          7,835   57,958          94,412
    Segment earnings (loss)     7,987        (2,055)    4,146          31,813
    Gross margin                  49%            15%      37%             49%

Medical Isotopes revenues increased $20.1 million or 256% in the fourth
quarter of fiscal 2010 compared with the same quarter in fiscal 2009
primarily due to the restart of the NRU reactor, which occurred in
late-August. The impact of the NRU reactor-based isotopes was partially
offset by a 7% decline in cyclotron isotopes as they returned to normal
levels.

Revenues of $58.0 million for the entire fiscal 2010 decreased by $36.4
million
or 39% compared with fiscal 2009 primarily due to the outage of the
NRU reactor, resulting in a 55% decrease in reactor-based isotope revenues.
The decrease in reactor-supplied revenues was partially offset by cyclotron
product revenues, which were 22% higher in fiscal 2010 compared with fiscal
2009, mainly driven by demand for Thallium-201, which was used as a
substitute for Mo-99 due to shortages resulting from the NRU reactor shutdown
and disruption to supply from the High Flux Reactor in the Netherlands in
fiscal 2010.

Targeted Therapies

                                  Three months ended      Twelve months ended
                                          October 31               October 31
                                  2010          2009     2010            2009
    Consolidated Results
    (thousands of U.S.
    dollars, except where
    noted)
    Revenues                  $ 19,851        14,660   65,552          42,261
    Segment earnings (loss)      1,980         2,229    6,582             261
    Gross margin                   48%           42%      41%             38%

Targeted Therapies revenues increased $5.2 million or 35% in the fourth
quarter of fiscal 2010 compared with the same quarter in fiscal 2009
reflecting strong performance by TheraSphere(R) and CardioGen-82(TM)
products. Segment earnings decreased $0.3 million or 11% as increased
research and development spending on TheraSphere(R) and the decommissioning
of a production facility in Fleurus, Belgium offset the contribution from
stronger product sales.

Revenues of $65.6 million in fiscal 2010 increased by $23.3 million or
55% compared with fiscal 2009. The increase was due to the continued strong
performance of a number of products, primarily CardioGen-82(TM) along with
the global performance of TheraSphere(R) which grew by 40% in 2010.

Sterilization Technologies

                                  Three months ended      Twelve months ended
                                          October 31               October 31
                                  2010          2009     2010            2009
    Consolidated Results
    (thousands of U.S.
    dollars, except where
    noted)
    Revenues                  $ 38,083        28,916  116,842          94,590
    Segment earnings (loss)     17,706        13,203   46,861          35,085
    Gross margin                   60%           57%      54%             53%

Sterilization Technologies revenues increased $9.2 million or 32% in the
fourth quarter of fiscal 2010 compared with the same quarter in fiscal 2009
as a result of increased shipments of Co-60 and the sale of one production
irradiator. As a result of higher revenue, segment earnings increased by $4.5
million
or 34%.

Revenues of $116.8 million in fiscal 2010 increased $22.2 million or 24%
compared with fiscal 2009. The increase was primarily due to increased volume
and pricing of Co-60 and the shipment of two production irradiators in fiscal
2010, compared with one in fiscal 2009.

Corporate and Other

Corporate and Other recorded a loss of $9.5 million in the fourth quarter
of fiscal 2010, up $1.7 million or 22% compared with a loss of $7.8 million
in the fourth quarter of fiscal 2009. The increase in the operating loss was
primarily due to higher costs associated with transition activities, higher
annual incentive costs, mark-to-market valuation of deferred share units, and
unfavourable operational foreign exchange impact.

A segment loss of $66.1 million for Corporate and Other was recorded in
fiscal 2010, up $25.2 million or 62% compared with fiscal 2009. The increase
in the operating loss was mainly due to higher SG&A costs associated with
transition and strategic repositioning activities, and a non-cash foreign
exchange loss of approximately $27 million primarily resulting from the
revaluation of $450.0 million of proceeds from the sale of MDS Analytical
Technologies that were held in a Canadian dollar functional currency entity
in U.S. dollars to fund the substantial issuer bid.

Discontinued Operations

Nordion recorded an operating loss of $3.2 million in the fourth quarter
of fiscal 2010, compared with an operating loss of $7.3 million in the fourth
quarter of fiscal 2009. The decrease was primarily due to completion of the
strategic repositioning in fiscal 2010.

An operating loss of $62.0 million was recorded in fiscal 2010, compared
with a loss of $91.3 million in fiscal 2009. The operating loss in fiscal
2010 was primarily a result of the MDS Pharma Services Early Stage business
whereas the operating loss in fiscal 2009 included the operating performance
of MDS Pharma Services Early Stage and Late Stage businesses, as well as MDS
Analytical Technologies.

Conference Call

Nordion will hold a conference call on Friday, January 21, 2011 at 9:30
am ET
to discuss its fourth quarter and fiscal 2010 results. This call will
be webcast live at www.nordion.com, and will be available after the
call in archived format at
www.nordion.com/investors/webcasts_and_presentations.asp. To
participate, please dial +1-866-223-7781 (toll-free North America) or
+1-416-340-8018 (International).

Nordion's 2010 Annual Report and Annual Information Form, and the 2011
Management Proxy Circular can be accessed on the Company's website at
www.nordion.com/investors/annual_reports.asp.

About Nordion Inc.

Nordion Inc. (TSX: NDN; NYSE: NDZ) is a global specialty health science
company that provides market-leading products and services used for the
prevention, diagnosis and treatment of disease. We are a leading provider of
medical isotopes, targeted therapies and sterilization technologies that
benefit the lives of millions of people in more than 60 countries around the
world. Our products are used daily by pharmaceutical and biotechnology
companies, medical-device manufacturers, hospitals, clinics and research
laboratories. Nordion has more than 600 highly skilled employees in four
locations. Find out more at www.nordion.com.

Caution Concerning Forward-Looking Statements

From time to time, we make written or oral forward-looking statements
within the meaning of certain securities laws, including under applicable
Canadian securities laws and the "safe harbour" provisions of the United
States Private Securities Litigation Reform Act of 1995. This document
contains forward-looking statements including the strategy of the continuing
businesses, as well as statements with respect to our beliefs, plans,
objectives, expectations, anticipations, estimates and intentions. The words
"may", "could", "should", "would", "outlook", "believe", "plan",
"anticipate", "estimate", "project", "expect", "intend", "indicate",
"forecast", "objective", "optimistic", and words and expressions of similar
import, are intended to identify forward-looking statements.

By their very nature, forward-looking statements involve inherent risks
and uncertainties, both general and specific, which give rise to the
possibility that predictions, forecasts, projections and other
forward-looking statements will not be achieved. We caution readers not to
place undue reliance on these statements as a number of important factors
could cause our actual results to differ materially from the beliefs, plans,
objectives, expectations, anticipations, estimates and intentions expressed
in such forward-looking statements. These factors include, but are not
limited to: management of operational risks; our ability to secure a reliable
supply of raw materials, particularly cobalt and critical medical isotopes;
the effects of competition in the markets in which we operate; our ability to
manage long-term supply commitments; our reliance on one customer for the
majority of our sales of medical isotopes; our ability to maintain regulatory
approval for the manufacturing, distribution and sale of our products; the
strength of the global economy, in particular the economies of Canada, the
U.S., the European Union, Asia, and the other countries in which we conduct
business; the stability of global equity markets; assets and liabilities that
we retained from the businesses sold; obligations retained and projected
adjustments thereto; successful implementation of structural changes,
including restructuring plans; our ability to complete other strategic
transactions and to execute them successfully; our ability to negotiate
future credit agreements, which may or may not be on terms favorable to us;
the impact of the movement of the U.S. dollar relative to other currencies,
particularly the Canadian dollar and the euro; changes in interest rates in
Canada, the U.S., and elsewhere; the timing and technological advancement of
new products introduced by us or by our competitors; our ability to manage
our research and development; the impact of changes in laws, trade policies
and regulations including health care reform, and enforcement thereof;
regulatory actions; judicial judgments and legal proceedings, including legal
proceedings described in this document; our ability to maintain adequate
insurance; our ability to successfully realign our organization, resources
and processes; our ability to retain key personnel; our ability to have
continued and uninterrupted performance of our information technology and
financial systems; our ability to compete effectively; the risk of
environmental liabilities; new accounting standards that impact the policies
we use to report our financial condition and results of operations;
uncertainties associated with critical accounting assumptions and estimates;
the possible impact on our businesses from third-party special interest
groups; our ability to negotiate and maintain collective-bargaining
agreements for certain of our employees; natural disasters; public health
emergencies and pandemics; international conflicts and other developments
including those relating to terrorism; other risk factors described in
section 5 of our AIF; and our success in anticipating and managing these
risks.

The foregoing list of factors that may affect future results is not
exhaustive. When relying on our forward-looking statements to make decisions
with respect to the Company, investors and others should carefully consider
the foregoing factors and other uncertainties and potential events. We do not
undertake to update any forward-looking statement, whether written or oral,
that may be made from time to time by us or on our behalf, except as required
by law.

    For further information:

    CONTACTS:
    INVESTORS:
    Ana Raman
    +1-613-595-4580
    investor.relations@nordion.com

    MEDIA:
    Tamra Benjamin
    +1-613-592-3400 x. 1022
    tamra.benjamin@nordion.com

For further information: CONTACTS: INVESTORS: Ana Raman, +1-613-595-4580, investor.relations at nordion.com; MEDIA: Tamra Benjamin, +1-613-592-3400 x. 1022, tamra.benjamin at nordion.com

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