SYGNIS to Present at the 11th Rodman & Renshaw Annual Global Investment Conference

HEIDELBERG, Germany - SYGNIS Pharma AG (Frankfurt: LIO; ISIN DE0005043509; Prime Standard) announced today that the company will present at the 11th Rodman & Renshaw Annual Global Investment Conference, September 9-11, 2009 at the New York Palace Hotel, New York. The presentation will be given by Prof. Karoly Nikolich, CEO of the SYGNIS subsidiary Amnestix Inc. on September 11, 2009 at 2:25 p.m. EDT (20:25 CET) in the Garrison Salon.

About SYGNIS Pharma

SYGNIS Pharma AG, headquartered in Heidelberg, is a specialty pharmaceutical company listed on the Prime Standard of the German stock exchange. The Company is focused on the research, development and marketing of innovative therapies for the treatment of disorders of the Central Nervous System. These include stroke, amyotrophic lateral sclerosis (ALS) and neurological disorders resulting from injuries of the brain or spinal cord. All these disorders are characterized by the fact that, as the disease progresses, nerve cells are damaged and die. Although there is great medical demand, there are currently no or only inadequate treatment options available.

One of the central elements in this value-creation chain is the continued development of the existing product pipeline. This is achieved by testing the Company’s proprietary compounds, which are already under development in a number of further CNS indications (”line extension”). Within specific R&D programs at SYGNIS, new pre-clinical drug candidates are identified and evaluated as well as early-stage projects are initiated for the purpose of partnering.

Disclaimer

Some statements included in this press release, relating neither to proven financial results nor other historical data, should be viewed as forward-looking, i.e. not definite. Such statements are mainly predictions of future results, trends, plans or goals. These statements should not be considered to be total guarantees since given their very nature they are subject to known and unknown risks and imponderability and can be affected by other factors as a consequence of which the actual results, plans and goals of SYGNIS Pharma AG may deviate greatly from the established conclusions or implied predictions contained in such statements. SYGNIS does not undertake to publicly update or revise these statements in the light of new information or future results or for any other reason.

For further information, please contact: Dr. Franz-Werner Haas Vice President Operations +49(0)-6221-454-812 franz-werner.haas@sygnis.de Media-Contact: Julia Phillips Financial Dynamics Tel.: +44(0)20-7269-7187

Source: SYGNIS Pharma AG

For further information, please contact: Dr. Franz-Werner Haas, Vice President Operations, +49(0)-6221-454-812, franz-werner.haas at sygnis.de; Media-Contact: Julia Phillips, Financial Dynamics, Tel.: +44(0)20-7269-7187