Viroblock SA Reports Positive Results of Preclinical Studies in Antiviral Nasal Spray

By Prne, Gaea News Network
Monday, March 30, 2009

GENEVA, Switzerland - Viroblock SA has announced today that the first generation of
VCCD Tech antiviral nasal spray formulation is active against human
influenza. Viroblock’s patented Cholesterol Catalytic Depletion Technology
(VCCD Tech) inactivates enveloped viruses during the extra-cellular phase, by
altering and destabilizing cholesterol-rich viral envelopes.

The two pre-clinical studies exposed ferrets to Influenza A
Wisconsin/67/2005 and influenza A Panama/2007/99 strains, and were conducted
by Retroscreen Virology Ltd, a recognized leader in the research and testing
of antiviral compounds and vaccines. Both the direct inoculation and the
natural transmission protocols have confirmed the effectiveness and the value
of the antiviral nasal spray.

These in-vivo campaigns confirm all in laboratory in-vitro
studies to date and demonstrate that VCCD Tech represents a breakthrough for
inactivating a number of enveloped viruses and their strains.

“Our depletion technology shows no toxicity at the dosage we
tested thus far and allegedly limits the development of any viral resistance,
and makes it effective on all families of enveloped viruses, such as human
and avian influenzas, SARS, AIDS, Ebola and smallpox viruses.”

“This is an exciting development period for Viroblock and the
most recent pre-clinical performance is a testament to our innovative and
cutting-edge technology, the quality of our team, board of directors and
investors.”

“We, at Viroblock, leverage all our technological assets for
rapidly developing the next generation of antiviral nasal sprays; I am also
confident that our technology will become an important element of pandemic
influenza preparedness efforts”.

“Our ability to deliver tailored antiviral formulations, which
can exist as colloidal suspensions, gels, creams, and aerosol sprays, opens
promising business opportunities and a bright future for Viroblock.”,
comments CEO Thierry Pelet.

About Viroblock SA

Viroblock SA is a Swiss start-up founded in 2005, which has become a
pioneer and world leader in the blocking virus transmission technology.

Its patented VCCD technology allegedly inactivates all
families and strains of enveloped viruses, like human and avian influenzas,
RSV, SARS, AIDS, Ebola and smallpox viruses, and leverages a mechanism of
action that limits the development of any viral resistance and toxicity. VCCD
Tech products exist as colloidal suspensions, gels, creams, and aerosol
sprays, having specific mechanical, physical and chemical properties

The W.A. De Vigier Foundation nominated Viroblock SA as one of
the 10 best technology projects of the year 2006, and the Swiss Tech Tour
2007 Selection Committee has rated Viroblock SA as part of the top 50
technology companies in Switzerland.

Viroblock was founded by Dr. Donald F. H. Wallach who was a
worldwide expert in artificial and bio-membranes, and non-phospholipid
vesicles.

Additional information is available on the company’s website
at www.viroblock.com

Contact:

Thierry Pelet
Chief Executive Officer
Viroblock SA
Phone: +41-22-884-83-44
E-Mail: t.pelet@viroblock.com

Source: Viroblock SA

Contact: Thierry Pelet, Chief Executive Officer, Viroblock SA, Phone: +41-22-884-83-44, E-Mail: t.pelet at viroblock.com

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