Zimmer Introduces the Maxera(TM) Cup for More Active Patients

By Zimmer Holdings Inc., PRNE
Tuesday, May 31, 2011

COPENHAGEN, Denmark, June 1, 2011 -

- Large Diameter, Ceramic-on-Ceramic Hip Solution Provides Increased
Range of Motion and Stability

Zimmer Holdings, Inc. (NYSE and SIX: ZMH), a global leader in
musculoskeletal care, today introduced the Maxera Cup, a new hip solution
designed for younger and more active patients. The Maxera Cup features a
large diameter femoral head that provides an increased range of motion and
enhanced stability. The full hemispherical design of the new cup provides
stable fixation. The Maxera Cup incorporates BIOLOX(R) * delta Ceramic
Technology which provides low wear, high fracture resistance and excellent
bio-compatibility, making the cup an appropriate choice for the treatment of
younger and more active patients.

The Maxera Cup is offered with BIOLOX delta and BIOLOX OPTION Large
Diameter Heads (with sizes of 32mm up to 48mm). Large diameter heads offer a
high degree of stability due to the increased displacement distance and allow
a greater technical range of motion compared to conventional small diameter
(28mm) articulation. This results in improved functionality and stability,
along with a reduced risk of dislocation [1-6]. A recent clinical study
demonstrates that there is a significant decrease in impingement,
subluxation, and dislocations for 36mm ceramic-on-ceramic coupling (0.88%)
when compared to 28mm femoral heads (4.64%) in total hip replacement [7].

Optimized Articulation Technology

The Maxera Cup is a ceramic-on-ceramic system based on the BIOLOX delta
Alumina Matrix Composite, offering low wear, excellent biocompatibility and
toughness as well as chemical and hydrothermal stability [10]. The BIOLOX
delta Ceramic Surface has also been proven to reduce friction and lower wear,
while its favourable wetting characteristics contribute to better lubrication
[8, 9]. A ceramic-on-ceramic system forms an appropriate alternative to
metal-on-metal articulation for patients who may be sensitive to specific
metal ions and/or metal wear [10].

Besides its excellent biocompatibility, increased stability, and
increased range of motion, the Maxera Cup is characterized by stable
fixation. Its 180 degree full hemispherical design is appointed with three
sets of paired anti-rotation fins that ensure additional rotational stability
[11]. The cup provides a familiar surgical technique for orthopaedic surgeons
who can choose the desired press-fit based on patients' bone quality using
Maxera Cup instrumentation.

The Maxera Cup is not available for commercial distribution in the United
States
. For more information about the advantages of the Maxera Cup please
visit maxera.zimmer.com.

* BIOLOX(R) delta Ceramic is a trademark of CeramTec AG

About the Company
Founded in 1927 and headquartered in Warsaw, Indiana, Zimmer designs,
develops, manufactures and markets orthopaedic reconstructive, spinal and
trauma devices, dental implants, and related surgical products. Zimmer has
operations in more than 25 countries around the world and sells products in
more than 100 countries. Zimmer's 2010 sales were approximately $4.2 billion.
The Company is supported by the efforts of more than 8,000 employees
worldwide.

Zimmer Safe Harbor Statement

This press release contains forward-looking statements within the safe
harbor provisions of the Private Securities Litigation Reform Act of 1995
based on current expectations, estimates, forecasts and projections about the
orthopaedics industry, management's beliefs and assumptions made by
management. Forward-looking statements may be identified by the use of
forward-looking terms such as "may," "will," "expects," "believes,"
"anticipates," "plans," "estimates," "projects," "assumes," "guides,"
"targets," "forecasts," and "seeks" or the negative of such terms or other
variations on such terms or comparable terminology. These statements are not
guarantees of future performance and involve risks, uncertainties and
assumptions that could cause actual outcomes and results to differ
materially. For a list and description of such risks and uncertainties, see
our periodic reports filed with the U.S. Securities and Exchange Commission.
We disclaim any intention or obligation to update or revise any
forward-looking statements, whether as a result of new information, future
events or otherwise, except as may be set forth in our periodic reports.
Readers of this document are cautioned not to place undue reliance on these
forward-looking statements, since, while we believe the assumptions on which
the forward-looking statements are based are reasonable, there can be no
assurance that these forward-looking statements will prove to be accurate.
This cautionary statement is applicable to all forward-looking statements
contained in this document.

References

[1] Amstutz et al., Prevention and treatment of dislocation after total
hip replacement using large diameter balls. Clin Orthop Relat Res., Dec 2004,
(429): 108-16

[2] Cuckler et al., Large versus small femoral heads in metal-on-metal
total hip arthroplasty, J Arthroplasty, Vol 19, Issue 8, Suppl 3, Dec 2004:
41-44

[3] Hummel et al., Decreased Dislocation After Revision Total Hip
Arthroplasty Using Larger Femoral Head Size and Posterior Capsular Repair, J
Arthroplasty, Vol 24, Issue 6, Suppl 1, Sept 2009: 73-76

[4] Dowd et al., Large Femoral Heads Can Help Reduce Risk of Dislocation
in Total Hip Arthroplasty, J Arthroplasty, Vol 23, Issue 2, Feb 2008: 318

[5] Peters et al., Reduction in Early Dislocation Rate With
Large-Diameter Femoral Heads in Primary Total Hip Arthroplasty, J
Arthroplasty, Vol 22, Issue 2, Feb 2007: 312

[6] Howie et al., A randomised controlled trial of large metal on highly
cross-linked polyethylene articulations in primary and revision total hip
replacement, 40th Advances in Arthroplasty, 202, Cambridge, MA, 2010.

[7] Zagra L, et al: THA ceramic-ceramic coupling: The evaluation of the
dislocation rate with bigger heads. In Lazennec JY, Dietrich M (eds):
Bioceramics in Joint Arthroplasty, Darmstadt, Steinkopff, 2004, 163-168

[8] Kuntz M, Validation of a New High Performance Alumina Matrix
Composite for use in Total Joint Replacement. Seminars in Arthroplasty, 2006;
17: 141-145

[9] Fisher et al., Wear of Highly Crosslinked Polyethylene against Cobalt
Chrome and Ceramic Femoral Heads, 11th International CeramTec Symposium,
185-88, New York, 2006

[10] CeramTec GmbH; internal data on file.

[11] Baleani et al., Initial stability of a cementless acetabular cup
design: experimental investigation on the effect of adding fins to the rim of
the cup. Artif Organs, Aug 2001, 25(8): 664-9

Media, Garry R. Clark, +1-574-372-4493, garry.clark at zimmer.com, Investors, Robert J. Marshall Jr., +1-574-371-8042, robert.marshall. at zimmer.com

YOUR VIEW POINT
NAME : (REQUIRED)
MAIL : (REQUIRED)
will not be displayed
WEBSITE : (OPTIONAL)
YOUR
COMMENT :