Frost & Sullivan European Gastroenterology Technology Implementation of the Year Award Bestowed on Crospon

LONDON -

The Frost & Sullivan “2009 European Gastroenterology Technology Implementation of the Year Award,” is presented to Ireland-based Crospon for successfully using the impedance planimetry technique in its novel EndoFLIP(R) (endoluminal functional lumen imaging probe) imaging system.

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“With EndoFLIP(R), Crospon has addressed the urgent need for a clinically acceptable diagnostic platform targeting gastroesophageal reflux disease (GERD),” states Frost & Sullivan Research Analyst Prasanna Vadhana Kannan. “This integrated solution facilitates real-time imaging of the lower oesophageal sphincter in less than ten minutes.”

The system uses a simple technique - impedance planimetry - that transforms an impedance measurement into an area measurement. It, therefore, provides a more physiologically relevant diagnostic test for GERD.

The EndoFLIP(R) system also assists surgeons in the assessment of the degree of surgical tightening of the sphincter region during surgery. The evaluation of the gastroesophageal junction by EndoFLIP(R), in tandem with direct endoscopic visualisation, heralds the emergence of a novel paradigm of diagnostic assessment known as functional endoscopy.

“Crospon’s solution is easy to deploy and is also cost-effective,” states Kannan. “Moreover, the components of the imaging tool enable precise measurement of the distensibility and functional diameter of the sphincter region, thereby serving as an indispensable tool for gastroenterologists.”

Crospon has submitted an application to the FDA for EndoFLIP(R)’s clearance in the US market. It has already received CE mark certification from the National Standards Authority of Ireland.

The Company recently announced that it has agreed to a worldwide distribution deal for EndoFLIP(R). The agreement with Dutch company, Medical Measurement Systems, one of the world’s leading companies in the development and distribution of medical gastrodiagnostic systems will result in first customer shipments into Europe during the summer.

The company is in the process of conducting more advanced trials on the system. It aims to demonstrate the important role that EndoFLIP(R) could play in determining the biomechanical properties of the gastroesophageal junction in GERD patients.

“Nearly 6-7 patents covering different applications of the EndoFLIP(R) platform have been filed,” comments Kannan. “Crospon is engaged in an active partnership with Northwestern University for conducting clinical studies related to EndoFLIP(R)’s applicability.”

Frost & Sullivan’s Technology Implementation Award is bestowed upon a company, which makes effective and an innovative use of an existing technology, which has resulted in innovation(s) that have brought or are expected to bring significant contributions to the industry in terms of adoption, change, and competitive posture. This award recognises the quality and depth of a company’s research and development program as well as the vision and risk-taking that enabled it to undertake such an endeavor.

Frost & Sullivan Best Practices Awards recognise companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research in order to identify best practices in the industry.

About Crospon

Crospon formed in 2006, is a medical device company focused on the monitoring and treatment of gastroesophageal reflux disorder (GERD). Company co-founder and CEO, John O’Dea, previously co-founded Caradyne, a respiratory products company which was acquired by Respironics Inc in 2004.

Crospon recently won a Connaught Business Achievers Award for 2008 in the ‘Ones to Watch’ category and the company’s Smart Drug Delivery Patch in conjunction with HP was listed in Popular Science’s magazines annual ‘Best of What’s New’ for 2008.

Crospon Contact Information: John McGuinness Murray Consultants +353-1-498-0361 jmcguinness@murrayconsult.ie

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, enables clients to accelerate growth and achieve best in class positions in growth, innovation and leadership. The company’s Growth Partnership Service provides the CEO and the CEO’s Growth Team with disciplined research and best practice models to drive the generation, evaluation and implementation of powerful growth strategies. Frost & Sullivan leverages over 45 years of experience in partnering with Global 1000 companies, emerging businesses and the investment community from 31 offices on six continents. To join our Growth Partnership, please visit www.frost.com.

Frost & Sullivan Contact: Jasmine Malone - Promotions Coordinator Phone: +44-207-915-7869 E-Mail: jasmine.malone@frost.com

Source: Frost & Sullivan

Jasmine Malone - Promotions Coordinator of Frost & Sullivan, +44-207-915-7869, jasmine.malone at frost.com; or John McGuinness of Murray Consultants, +353-1-498-0361, jmcguinness at murrayconsult.ie, for Crospon / Logo: https://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO