MarketAxess Announces Seventh Annual Charity Trading Day

Trading Revenues to Benefit Emerging Markets Charities

NEW YORK and LONDON, September 20, 2010 - MarketAxess Holdings Inc. (Nasdaq: MKTX), the operator of a leading
electronic trading platform for U.S. and European high- grade corporate
bonds, emerging markets bonds and other fixed income securities, today
announced that its seventh annual Charity Trading Day will be held on
September 23, 2010. MarketAxess, in partnership with EMTA, will donate all
emerging markets revenues from the trading day to emerging markets charities.

"Since launching electronic trading for emerging markets bonds over eight
years ago, we are grateful to have developed many strong relationships within
the emerging markets trading community," said Richard M. McVey, Chairman and
Chief Executive Officer of MarketAxess. "We thank our investor and dealer
clients for their continued support of the Annual Charity Trading Day,
enabling us to provide valuable assistance to those in need in the emerging
markets."

Each year charities are selected as beneficiaries by emerging markets
industry benefit committees in New York and London. The charities that will
benefit from this year's donations include:

    -- Cotlands, a long-serving South African non-profit agency that
       continues to meet the needs of children affected by HIV/AIDS.

    -- Children of the Andes, which supports street children in Colombia.

    -- Downside Up, which provides support and education for children in
       Russia with Down's Syndrome.

    -- EMpower, which connects the emerging markets community with innovative
       grassroots organizations enabling young people to lead healthy,
       productive lives.

    -- Fonkoze, which offers micro finance services aimed at improving the
       economic and social conditions in Haiti.

    -- Health Unlimited, which works with indigenous communities and
       communities affected by conflict and political instability to achieve
       better health.

    -- NESST, an organization that provides financial and capacity-building
       support to social enterprises in Central Europe and Latin America.

    -- Orphaned Starfish Foundation, an organization dedicated to working
       with orphans and disadvantaged children throughout Latin America.

    -- WorldFund, which provides financial, managerial and technical
       assistance to partner schools in impoverished Latin American
       neighborhoods.

The total amount of this year's donations will be announced at the
emerging markets debt industry's annual London and New York benefits, which
are scheduled for Friday, October 1, 2010, and Thursday, December 2, 2010,
respectively.

About MarketAxess

MarketAxess operates a leading electronic trading platform that enables
investment industry professionals to efficiently trade corporate bonds and
other types of fixed-income instruments. MarketAxess' patented trading
technology allows institutional investor clients to request competitive,
executable bids or offers from multiple broker-dealers simultaneously, and to
execute trades with the broker-dealer of their choice. Approximately 800
institutional investors are active users of the MarketAxess trading platform,
accessing the global liquidity provided by MarketAxess' 80 broker-dealer
clients in U.S. high-grade corporate bonds, European bonds, high yield and
emerging markets bonds, agency bonds and credit default swaps. MarketAxess
also offers a number of trading-related products and services, including:
market data to assist clients with trading decisions; connectivity solutions
that facilitate straight-through processing; technology services to optimize
trading environments; and execution services for exchange-traded fund
managers and other clients.

MarketAxess maintains its headquarters in New York and has offices in
London, Chicago and Salt Lake City. For more information, please visit
www.marketaxess.com.

About EMTA

Founded in 1990, EMTA (formerly the Emerging Markets Traders Association)
is a not-for-profit corporation dedicated to promoting the orderly
development of fair, efficient and transparent trading markets for emerging
markets instruments, and the integration of the emerging markets into the
global financial marketplace.

MarketAxess: Trey Gregory, MarketAxess Holdings Inc., +1-212-813-6382, or EMTA: Jonathan Murno, +1-646-289-5413