Agendia Presents Broad Array of Predictive and Prognostic Studies on Breast and Colorectal Cancers at ASCO 2010 Annual Meeting
By Agendia B.v., PRNEThursday, June 3, 2010
HUNTINGTON BEACH, California and AMSTERDAM, June 4, 2010 - Agendia, a world leader in molecular cancer diagnostics, today announced
that researchers from Agendia and leading academic centers in the U.S. and
Europe will present data from multiple studies concerning Agendia's assays
MammaPrint(R), BluePrint(TM), and ColoPrint(TM) at the American Society of
Clinical Oncology Annual Meeting, June 4 - 8, 2010, at McCormick Place in
Chicago. MammaPrint, the company's lead product, is the only FDA-cleared
breast cancer recurrence test. FDA clearance requires clinical and analytical
validation and full transparency to ensure patient safety issues are
addressed. The company anticipates launching its prognostic colon cancer test
ColoPrint in late 2010.
The study results underpin the broad predictive and prognostic
power of MammaPrint and highlight prospective and independently validated
data on ColoPrint. Visitors can meet the Agendia team in booth #18018 and
study results will be discussed at the following sessions:
Breast Cancer Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract #10615 Substratification of 70-gene high-risk breast cancers with a validated 80-gene molecular subtyping profile F. de Snoo, B. Chan, P. Roepman, R. A. Bender, A. Glas Time: 8:00 AM - 12:00 PM Location: S Hall A2 Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract # 540 Gene signatures as predictors of response to neoadjuvant chemotherapy (NCT) with docetaxel, doxorubicin, cyclophosphamide (TAC), or AC and nab-paclitaxel (nab-P) and carboplatin plus or minus trastuzumab in patients (pts) with stage II-III and inflammatory breast cancer (IBC) G. Somlo, P. H. Frankel, L. Vora, S. Lau, T. H. Luu, L. Kruper, J. Yim, Y. Yen, F. de Snoo, R. A. Bender Time: 2:00 PM - 6:00 PM Location: S Hall A2 Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract # 561 Evaluation of the 70-gene prognosis MammaPrint signature for the prediction of prognosis of breast cancer independently from histologic grade M. Knauer, E. J. Rutgers, S. Mook, J. Wesseling, L. J. van 't Veer Time: 2:00 PM - 6:00 PM Location: S Hall A2 Date: Monday, June 7, 2010 POSTER DISCUSSION - Abstract # 1520 Effect of screening on the detection of good and poor prognosis breast cancers Y. Shieh, L. Esserman, E. J. Rutgers, M. Knauer, V. Retel, S. Mook, A. Glas, S. C. Linn, F. E. van Leeuwen, L. van't Veer Time: 2:00 PM - 6:00 PM / 5:00 PM - 6:00 PM (discussion in E451b) Location: E450b Colon Cancer Date: Monday, June 7, 2010 POSTER PRESENTATION - Abstract # TPS199 The PARSC trial, a prospective study for the assessment of recurrence risk in stage II colon cancer (CC) patients using ColoPrint R. Salazar, J. Marshall, L. Stork-Sloots, I. Simon, M. Lutke Holzik, J. Tabernero, J. J. Van Der Hoeven, F. Bibeau, R. Rosenberg Time: 8:00 AM - 12:00 PM Location: S Hall A2 Date: Tuesday, June 8, 2010 POSTER DISCUSSION - Abstract # 3513 Independent validation of a prognostic genomic profile (ColoPrint) for stage II colon cancer (CC) patients R. Rosenberg, M. Maak, U. Nitsche, T. Schuster, B. Kuenzli, M. Snel, I. Simon, K. Janssen, H. Friess Time: 11:00 AM - 12:00 PM Location: S 406 (Vista Room)
About MammaPrint(R)
MammaPrint is the first and only breast cancer recurrence test
cleared by the U.S. Food and Drug Administration (FDA). FDA clearance under
the in vitro diagnostic multivariate index assay (IVDMIA) guidelines requires
clinical and analytical validation and reporting systems to ensure patient
safety issues are addressed. Highly accurate, MammaPrint identifies patients
with early metastasis risk - patients who are likely to develop metastases
within five years following surgery. Several authoritative studies have shown
that chemotherapy particularly reduces early metastasis risk. In planning
treatment, the MammaPrint test results provide doctors with a clear rationale
to assess the benefit of chemotherapy in addition to other clinical
information and pathology tests.
All MammaPrint tests are conducted in Agendia's CAP-accredited and CLIA
compliant service laboratories.
About Agendia
Agendia is at the forefront of the personalized medicine
revolution, striving to bring more effective, individualized treatments
within reach of patients. Building on a cutting-edge genomics platform for
tumor gene expression profiling, the company's tests help physicians more
accurately tailor cancer treatments. Agendia markets four products, with
several new genomic tests under development. In addition, Agendia
collaborates with pharmaceutical companies to develop highly effective
personalized drugs in the area of oncology. Agendia is based in Huntington
Beach, California, and in Amsterdam, The Netherlands.
MEDIA CONTACTS: Hans Herklots, Agendia, +31-20-462-1557 Office, +31-620-083-509 Mobile, hans.herklots at agendia.com; Valerie Delva, Ricochet Public Relations, +1-212-679-3300 x128 Office, +1-917-755-6194 Mobile, vdelva at ricochetpr.com
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