Philips Receives CE Mark for First New Imaging Modality in 10 Years

By Royal Philips Electronics, PRNE
Monday, January 24, 2011

Versatile whole body PET/MR imaging system enables clinicians to see chronic diseases earlier and monitor efficacy of treatment

ANDOVER, Massachusetts, January 25, 2011 - Royal Philips Electronics (NYSE: PHG, AEX: PHI) is announcing CE marking
for the industry's first commercially available whole body PET/MR imaging
system, the Ingenuity TF PET/MR*. This new system, being launched as the
first new Philips modality in ten years, integrates the molecular imaging
capabilities of PET (positron emission tomography) with the superior soft
tissue contrast of MR (magnetic resonance) to image disease cells as they
proliferate in soft tissue. Since the Ingenuity TF PET and MR scanners are
placed only three meters apart and the patient table rotates to allow the
patient to be scanned by each modality, the system can also acquire separate
PET and MR images.

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Clinicians anticipate using the Ingenuity TF PET/MR to screen patients at
high-risk for heart disease to ultimately treat diseased cells prior to the
formation of dangerous coronary plaques. The system may also be used to scan
patients to detect tumor formation/recurrence. Since the Ingenuity TF PET/MR
provides the best of Astonish TF PET and 3T MR, it is also possible to track
whether a drug is reaching a tumor or plaque and monitor efficacy on a
potential cellular level. In addition to greater visualization of disease
process, the system can also produce up to 70% less ionizing radiation than
PET/CT. (i, ii)

The Future of Personalized Medicine

The combination of advances in high resolution MR and the ability to
combine MR and PET into one whole body system has lead healthcare
professionals to believe that the Ingenuity TF PET/MR will help identify
disease sooner and make personalized medicine a reality.

"It's rare to develop a modality that completely revolutionizes imaging;
usually, companies can only strive for clearer images at a lower dose. With
the Ingenuity TF PET/MR, researchers are experiencing breakthroughs on
multiple fronts. They are able to effectively image the prostate for the
first time and detect deadly cancers in organs such as the pancreas at a
significantly earlier stage," said Dominic Smith, vice president of
marketing, Computed Tomography and Nuclear Medicine for Philips Healthcare.
"The Ingenuity TF PET/MR provides researchers and clinicians an unprecedented
opportunity to make earlier diagnoses and personalize treatments for oncology
and cardiology."

University of Geneva

The University Hospital of Geneva houses Europe's first combined whole
body PET/MR system. Professor Osman Ratib, chief of Nuclear Medicine,
University of Geneva, commented, "Our validation tests show that bringing the
two modalities together improves the quality and accuracy of diagnoses. The
molecular imaging provided by PET in conjunction with the anatomy and tissue
characterization of MR has enabled us to see the function and metabolism of
tissue more precisely than ever before. The clinical cases have already shown
the advantages of being able to perfectly superimpose PET over MR images to
detect lesions in various organs. Previously, this was not possible because
the two studies took place at different times, with different conditions and
with different patient positions. We are confident that PET/MR will become a
valuable asset in our department and we look forward to being able to use it
in our clinical routine."

Professor Zahi Fayad, Professor of Radiology and Medicine (Cardiology),
and director, Translational and Molecular Imaging Institute, Mount Sinai
School of Medicine in New York, New York and Prof. Joerg Steinbach,
Director, Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf
(HZDR), Dresden, Germany also installed the Ingenuity TF PET/MR. In 2011,
additional installations are expected worldwide.

*Pending 510(k), not available for sale in the U.S.

About Royal Philips Electronics

Royal Philips Electronics of the Netherlands (NYSE: PHG, AEX: PHI) is a
diversified health and well-being company, focused on improving people's
lives through timely innovations. As a world leader in healthcare, lifestyle
and lighting, Philips integrates technologies and design into people-centric
solutions, based on fundamental customer insights and the brand promise of
"sense and simplicity." Headquartered in the Netherlands, Philips employs
more than 119,000 employees in more than 60 countries worldwide. With sales
of EUR 25.4 billion in 2010, the company is a market leader in cardiac care,
acute care and home healthcare, energy efficient lighting solutions and new
lighting applications, as well as lifestyle products for personal well-being
and pleasure with strong leadership positions in flat TV, male shaving and
grooming, portable entertainment and oral healthcare. News from Philips is
located at www.philips.com/newscenter.

(i) Brix G, Lechel U, Glatting G, Ziegler SI, Munzing W, Muller SP,et al.
Radiation exposure of patients undergoing whole-body dualmodality 18F-FDG
PET/CT examinations. J Nucl Med 2005;46:608-13.

(ii) Brix G, Beyer T. PET/CT: dose-escalated image fusion? Nuklearmedizin
2005;44:S51-57.

Philips Healthcare, Steve Kelly, +1-425-487-7479, steve.kelly at philips.com

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