Concentric Medical Announces Product and Procedure Reimbursement as Well as Full Commercialization of the Merci Retriever(R) in Japan

By Concentric Medical Inc., PRNE
Sunday, October 3, 2010

MOUNTAIN VIEW, California, October 4, 2010 - Concentric Medical, Inc., the global leader in devices for clot removal
in ischemic stroke patients, today announced that the Merci Retriever(R) has
recently received both product and procedure reimbursement from the Japanese
Ministry of Health, Labor and Welfare. The Merci Retriever is a
catheter-based medical device that physicians at stroke centers use to remove
blood clots from the brains of patients suffering an ischemic stroke.

On May 4th, Concentric Medical announced the Shonin approval of the Merci
Retriever(R), Merci(R) Microcatheter, and Merci(R) Balloon Guide Catheter.

Nobuyuki Sakai, M.D., D.M.Sc., Director, Neurosurgery & Stroke Center at
Kobe City General Hospital said, "The Merci Retriever is quickly becoming a
very meaningful treatment option for acute stroke patients in Japan. The
initial cases at leading stroke institutions since Shonin approval have been
very successful. Reimbursement for the Merci Retriever and the mechanical
procedure are a critical part of making the Merci system available to all
neurosurgeons, neurologists, and hospitals in Japan that treat acute stroke

Century Medical, Inc. is the exclusive distribution partner for
Concentric Medical in Japan. The two companies worked together to obtain both
Shonin approval and reimbursement for the Merci Retriever, which is the first
device for clot removal for ischemic patients to be approved in Japan.

One of Concentric Medical's strategic objectives has been global
expansion. The incidence of stroke and the mortality and disability
associated with stroke are very significant issues for health care systems
across the world. Maria Sainz, President and CEO of Concentric Medical said,
"We are honored to be the first to offer a device solution for stroke
patients in Japan. Launching the Merci system in Japan is a very significant
milestone and a great new opportunity for growth for our company. With over
1,300 patients enrolled in clinical studies, we believe Merci has been proven
to be a very effective tool in revascularizing stroke patients."

Akira Hoshino, President and CEO of Century Medical, Inc. said, "Century
Medical is extremely excited to bring such a valuable and innovative therapy
to Japan. The reimbursement for both the Merci Retriever and procedure
related to mechanical thrombectomy with the Merci Retriever are an essential
part of the introduction of this new treatment. Century Medical is committed
to pioneering stroke treatment in Japan by working closely with physicians
and hospitals to make the Merci Retriever widely available for Japanese
stroke patients."

About Concentric Medical

Concentric Medical is located in Mountain View, California and is the
global leader in the development of endovascular devices for revascularizing
stroke patients. The company manufactures and markets solutions for ischemic
stroke: minimally invasive devices that are delivered into the brain to
restore blood flow by removing blood clots that cause ischemic stroke.
Concentric Medical's devices are available in over 500 leading stroke centers
around the world, and have been the subject of several clinical studies. For
more information about Concentric Medical, please visit

About Acute Ischemic Stroke

Stroke is the third leading cause of death in the developed world and the
leading cause of serious long-term disability. Ischemic stroke represents
over 85% of strokes and occurs when a blockage or clot develops in one of the
arteries supplying blood to the brain. In 2004 the FDA cleared Concentric
Medical's Merci Retriever for use in stroke patients who are ineligible for
IV-tPA or who fail to respond to IV-tPA therapy. This pioneering device
created a departure from the historic method of caring for stroke patients
and offered physicians and patients a long-awaited option for stroke

For more information about Concentric Medical, please visit

    Media Contact:

Concentric Medical, Inc., +1-650-938-2100, strokeinfo at

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