Ingenuity Systems and Sage Bionetworks Collaborate to Enable Predictive Disease Network Research

REDWOOD CITY, California, November 16, 2010 - Ingenuity(R) Systems, a leading provider of information solutions for
life science researchers, today announced a new collaboration with Sage
Bionetworks, a non-profit leader in predictive disease network research.
Under the collaboration, Sage will leverage IPA(R), Ingenuity's
industry-leading analysis software, and the Ingenuity(R) Knowledge Base of
structured biomedical Findings, to inform and enhance Sage's predictive
disease networks. Additionally, Sage's web portal will provide links to the
Ingenuity Knowledge Base and to IPA, to help visitors access timely,
context-rich biomedical information and better understand it in a biological
context. Sage's content, algorithms, and predictive disease networks will
also be made available within Ingenuity products like IPA(R).

The Ingenuity-Sage collaboration will support therapeutic area
researchers who are working to understand the complex developments in the
diagnosis, treatment, and etiology of diseases. Researchers will be able to
use the content and algorithms from Sage within IPA to analyze molecular
data, generate testable hypotheses, and build and visualize predictive
disease models. These models will enable researchers to more rapidly identify
and prioritize therapeutic targets for drug development and assess toxicity
of potential drug candidates.

"We're very excited about our collaboration with Ingenuity Systems,"
stated Stephen Friend MD, PhD, President, Sage Bionetworks. "Leveraging their
high-quality, expert-reviewed Ingenuity Knowledge Base Findings and their
powerful pathway analytics in our research will enhance and add functionality
to our predictive disease networks and algorithms."

"This represents a rare and precious opportunity to fundamentally advance
the field of predictive disease networks," said Doug Bassett, Chief Science
and Technology Officer at Ingenuity, "We're thrilled to be working with Sage
in this context, and excited at the value this can bring to Sage and
Ingenuity customers and partners. We are committed to providing researchers
with the very best predictive disease content and analytics within
Ingenuity's products."

About Ingenuity(R) Systems

Ingenuity Systems is a leading provider of information solutions and
custom services for life science researchers, computational biologists and
bioinformaticists, and life science industry suppliers. For more information
visit: www.ingenuity.com

About Sage Bionetworks

Sage Bionetworks is a nonprofit medical research organization established
in 2009 to revolutionize how researchers approach the complexity of human
biological information and the treatment of disease. Sage and its academic
and commercial partners employ multiple comprehensive molecular and clinical
datasets to create validated disease models that improve the speed and
efficiency of therapeutic drug development. Sage's vision is to create an
open access, integrative bionetwork evolved by contributor scientists working
to eliminate human disease. For more information visit: www.sagebase.org

Heidi Bullock, Director, Marketing of Ingenuity Systems, +1-650-381-5150