CAS REGISTRY(SM) Keeps Pace with Rapid Growth of Chemical Research, Registers 60 Millionth Substance

By Chemical Abstracts Service, PRNE
Tuesday, May 24, 2011

COLUMBUS, Ohio, May 25, 2011 -

- Therapeutic substance originates from Chinese patent, signifying role
of Pacific Rim research in the field of chemical and scientific publishing

Chemical Abstracts Service (CAS) (, the world's leader
in chemical information, announced today that a patent application claiming
compounds with potential therapeutic activity submitted to the State
Intellectual Property Office of the People's Republic of China (SIPO)
included the 60 millionth substance recorded in CAS REGISTRY

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CAS observed in 2009 that China surpassed all other nations as the top
producer of chemical patent applications. China still maintains the lead
today, and finding that the 60 millionth substance registered is from a SIPO
application reconfirms that observation.

Coming less than two years after CAS REGISTRY crossed the 50 million
mark, this second major milestone shows the continued acceleration of
chemical and scientific output across the globe. CAS scientists keep up with
this growth daily, by analyzing, organizing, and curating the output of
worldwide research in their native languages to maintain the completeness and
quality of CAS' premier substance collection.

The 60 millionth substance, a potential antiviral compound, was assigned
the CAS Registry Number(R) 1298016-92-8. The substance was discovered by the
Institute of Materia Medica, Chinese Academy of Medical Sciences
(, which is one of the key drug research
institutions in China. In the patent application, a team of inventors
prepared derivatives of 2-amino-1,3,4-thiadiazine.

"Our organization relies on CAS' research tool, SciFinder(R), as a
critical asset to our research team, helping to educate our R&D teams along
every step of the research process," said Pei Cheng Zhang, a professor at
Materia Medica. "Its database's rapid growth demonstrates its leadership
within the industry and breadth of coverage, making it paramount to our

"It seems fitting that the 60 millionth substance in CAS REGISTRY would
originate from within an Asian country, given the region's growing and
significant impact on scientific discovery in recent years," said Christine
, Vice President of Marketing at CAS. "This growth is illustrated not
only in the patent arena, but also with respect to journal literature, and
led CAS to expand coverage of Asian chemistry through the analysis of more
than 300 additional journal titles in the past three years from China, Japan,
and Korea alone."

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CAS REGISTRY is the most comprehensive collection of disclosed chemical
substance information in the world. It contains more than 60 million unique
organic and inorganic substances (,
such as alloys, coordination compounds, minerals, mixtures, polymers, and
salts, and more than 62 million sequences

About CAS

Chemical Abstracts Service (CAS), a division of the American Chemical
Society, is the world's authority for chemical information. Our databases are
curated and quality-controlled by CAS scientists, and recognized by chemical
and pharmaceutical companies, universities, government organizations, and
patent offices around the world as authoritative. By combining these
databases with advanced search and analysis technologies (SciFinder(R),
STN(R), and Science IP(R) products and services), CAS delivers the most
current, complete, and cross-linked digital information environment for
scientific discovery. Learn more at

Bob Sadowski, +1-614-447-3661, cas-pr at

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