Researchers Confirm Omega-3 EPA Required for Antidepressant Benefits

By Ocean Nutrition Canada Ltd., PRNE
Wednesday, December 15, 2010

DARTMOUTH, Canada, December 16, 2010 - Researchers at the University of Illinois at Chicago completed a review
of previously published research on antidepressant benefits of Omega-3
essential fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA). The review comprised a meta-analysis of 15 randomized, double-blind,
placebo-controlled studies in patients with depression and results were
presented at the recent annual meeting of the American College of

The analysis indicated that DHA alone did not appear to offer any
antidepressant benefits, where as patients taking EPA or a combination of EPA
and DHA experienced clear antidepressant benefits.

John M. Davis, M.D., research professor at the University of Illinois at
was quoted, "Our analysis clarifies the precise type of Omega-3 fatty
acid that is effective for people with depression and explains why previous
findings have been contradictory." Davis continued, "The EPA predominant
formulation is necessary for the therapeutic action to occur. The DHA
predominant formulation does not have antidepressant efficacy."

Jon Getzinger, Chief Sales and Marketing Officer, Ocean Nutrition Canada
(ONC) said, "Many consumers still do not fully understand the role of EPA and
DHA and the importance of having both EPA and DHA as part of a healthy diet.
It is believed that EPA plays a functional role in the brain, while DHA plays
a structural role." Getzinger continued, "Consuming DHA alone which
retrogrades poorly to EPA appears to be insufficient to provide the benefits
associated with the combination of EPA and DHA that is found in fish oil.
This analysis reinforces our understanding of the complementary roles that
both EPA and DHA have in the maintenance of healthy brain function, in
addition to the substantial scientific evidence supporting the benefits of
heart health."

According to the National Institute of Mental Health (NIMH),
approximately 20.9 million American adults suffer from various mood
disorders, or about 9.5 percent of the U.S. population age 18 and older in a
given year. NIMH also reports that data from the Agency for Healthcare
Research and Quality's 2006 Medical Expenditure Panel Survey indicates that
close to sixty billion dollars was spent on mental healthcare just in the
United States
during that year.

Omega-3 EPA and DHA continue to be among the most researched ingredients,
with over 14,000 published studies. As the amount of research demonstrating
the wide-ranging benefits of Omega-3 EPA and DHA increases, studies like this
and the recent recognition by European health authorities of a daily
reference intake of 250 mg/day of EPA and DHA, emphasize the fact that both
EPA and DHA from fish oil are important for overall well-being.

About Omega-3:

Omega-3 is a family of essential fatty acids (EFA), including EPA
(eicosapentaenoic acid), DHA (docosahexaenoic acid), and ALA (alpha-linolenic
acid). Oily fish (such as sardines, anchovies, mackerel, and salmon) are the
major known natural sources of Omega-3 EPA/DHA. ALA is found in plants, such
as flax and chia. It is important to note that EPA and DHA are the primary
contributors of the many health benefits associated with Omega-3. While the
body can convert ALA into EPA/DHA, it does so very inefficiently (typically
less than one percent), making it difficult to derive Omega-3-related health
benefits from plant sourced ALA. Recent analysis also supports the long held
belief that DHA alone is also insufficient to provide many of the benefits
attributed to fish oils that typically contain both EPA & DHA. Furthermore,
although Omega-3 EPA/DHA is important to overall good health, the human body
is not able to produce sufficient quantities on its own, so supplementation
is required, either by eating oily fish or foods fortified with Omega-3
EPA/DHA, or by taking fish oil supplements. Learn more about the health
benefits of Omega-3 EPA/DHA at

About Ocean Nutrition Canada Limited (ONC):

Ocean Nutrition Canada (ONC) is a privately held company, whose major
shareholder is Clearwater Fine Foods Incorporated. Clearwater Fine Foods
Incorporated is a diversified holding/investment company whose significant
holdings include a controlling interest in Clearwater Seafood's Limited
Partnership, the world's largest integrated shellfish harvester and

ONC is the world's largest supplier of Omega-3 EPA and DHA ingredients
from fish oil, marketed into the dietary supplement and food manufacturing
markets. To date MEG-3(R) ingredients have been included in over 90 billion
servings of food and supplement products worldwide. For more information
about ONC visit, and for information on the
health benefits of MEG-3(R) ingredients please visit

    For further information:

    Joanna Lane
    Ocean Nutrition Canada Ltd.
    Tel: +1-902-480-3288
    Cell: +1-902-488-0141

For further information: Joanna Lane, Ocean Nutrition Canada Ltd., Tel: +1-902-480-3288, Cell: +1-902-488-0141, jlane at

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